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NOT YET RECRUITING
NCT06745973
EARLY_PHASE1

An Exploratory Clinical Study Evaluating EPI-003 Injection for the Treatment of Chronic Hepatitis B

Sponsor: Epigenic Therapeutics, Inc

View on ClinicalTrials.gov

Summary

This study is an open-label, 2-Part (Single Ascending Dose \[Part 1\] And Dose Expansion) study that will evaluate the safety of EPI-003 administered to patients with chronic infection with HBV (CHB). EPI-003 is a liver-targeted antiviral therapeutic for intravenous (IV) injection that is capable of precise epigenetic modifications of the HBV genome without causing mutations in the gene sequence itself.

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

20

Start Date

2024-12-20

Completion Date

2026-12-31

Last Updated

2024-12-24

Healthy Volunteers

No

Interventions

DRUG

EPI-003

Intravenous (IV) infusion.

Locations (1)

Renji Hospital, Shanghai Jiao Tong University School of Medicine

Shanghai, China