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RECRUITING
NCT06747130
PHASE2/PHASE3

Efficacy of Montelukast in Preventing Transaminase Elevation in Adult Dengue Patients

Sponsor: Phramongkutklao College of Medicine and Hospital

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to learn if drug montelukast works to treat dengue in adults. It will also learn about the safety of drug montelukast . The main questions it aims to answer are: Does drug montelukast lower the incidence of liver enzyme elevations in participants ? What medical problems do participants have when taking drug montelukast ?

Official title: Efficacy of Montelukast in Preventing Transaminase Elevation in Adult Dengue Patients: a Randomized, Double-blind, Placebo Controlled, Superiority Trial

Key Details

Gender

All

Age Range

20 Years - Any

Study Type

INTERVENTIONAL

Enrollment

82

Start Date

2025-01-31

Completion Date

2027-01

Last Updated

2025-05-29

Healthy Volunteers

No

Interventions

DRUG

Montelukast

A 10-mg tablet will be given orally immediately and every day thereafter for 10 days or until recovery, defined as the discontinuation of the follow up appointment by the attending physicians, whichever is shorter

DRUG

Montelukast Placebo

A 10-mg tablet will be given orally immediately and every day thereafter for 10 days or until recovery, defined as the discontinuation of the follow up appointment by the attending physicians, whichever is shorter

Locations (1)

Phramongkutklao Hospital

Bangkok, Thailand