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Assessment of a Quantra-guided Transfusion Algorithm in Liver Transplantation
Sponsor: University Hospital, Toulouse
Summary
Liver transplantation carries a substantial risk of bleeding, making precise haemostasis control essential, although assessing coagulation remains challenging. Quantra, a bedside viscoelastic testing device using sonorheometric methods, offers an innovative approach to guiding haemostatic management during surgery. The study aims to determine whether a Quantra-guided transfusion can reduce transfusion and bleeding during liver transplantation when compared to a conventional transfusion approach.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
56
Start Date
2025-03-08
Completion Date
2027-03
Last Updated
2025-09-22
Healthy Volunteers
No
Conditions
Interventions
Transfusion algorithm based on Quantra®
In addition to routine coagulation tests, a Quantra Qstat® analysis will be performed at baseline (before incision), at the end of native liver dissection, and after unclamping of the venous anastomoses. In the event of bleeding, additional Quantra Qstat® analyses may be conducted until bleeding control is achieved. Transfusion and administration of blood-derived medications will be guided by the results of the Quantra Qstat® analyses.
Conventional transfusion algorithm
Transfusion and blood-derived medications will be guided by the results of routine coagulation tests.
Locations (1)
Toulouse University Hospital
Toulouse, France