Clinical Research Directory

Key Inclusion Criteria: * Diagnostic definition of acute alcohol-associated hepatitis based on well established standard disease markers * Able to provide written informed consent (either from patient or patient's legally authorized representative) * Male and female patients aged ≥18 years and ≤ 70 years of age * BMI ≥ 20 to ≤ 40 kg/m2 * Enterococcus faecalis testing * Susceptibility to NTR-101 * Women of child-bearing potential and male patients must agree to use a medically acceptable method of contraception/ birth control throughout the study duration. Key Exclusion Criteria: * Participants considered at high risk for alcohol withdrawal according to the clinical institute withdrawal assessment (CIWA-Ar) protocol * Participants taking systemic corticosteroids for a specified duration * Platelet count below specified ranges * INR and Serum creatinine levels above specified ranges * Active bacterial or viral infections * Other or concomitant cause(s) of liver disease as a result of other conditions * Co-infection with HIV * Positive urine drug screen * Any significant systemic or major illness other than liver disease that, in the opinion of the investigator, would preclude the patient from participating in and completing the study or might complicated or exacerbated by the proposed treatments or might confound assessment of investigational product * If female, known pregnancy, or has a positive serum pregnancy test, or lactating/ breastfeeding