Clinical Research Directory

Inclusion Criteria: * Diagnosed with dystonic tremor based on the MDS 2018 consensus * Duration of DT symptoms: ≥3 years of motor symptoms * If the patient is taking tremor medications, the medications should be stable for 28 days prior to informed consent * Good compliance and written informed consent Exclusion Criteria: * Any intracranial abnormalities that would prevent DBS surgery * Any significant mental illness that might affect the subject's ability to comply with the study protocol requirements (e.g., bipolar disorder, schizophrenia, mood disorders with psychotic features, Cluster B personality disorders) * Severe cognitive impairment, MOCA score \<24 * Any current substance or alcohol abuse according to DSM-V criteria * Any history of recurrent or unprovoked epileptic seizures; any prior movement disorder treatment involving intracranial surgery or device implantation; any history of hemorrhagic stroke; any significant medical condition that might interfere with the study procedures or could confound the assessment of study endpoints * Any terminal illness with a life expectancy of \<1 year