Clinical Research Directory

Clinical Pattern of Glanzemnn Thrombathenia in Children Attending Assiut University Children Hospital

Sponsor: Assiut University

Summary

there are major limitations of these GTR data, they were not obtained using a defined treatment protocol in a randomized manner and treatment effectiveness and safety were not assessed at multiple, consistent, predefined time points. Furthermore, the frequent use of multiple agents in GT and delays in obtaining platelets make it particularly difficult to attribute effectiveness to any one or more products effectiveness and safety of using rFVII in pediatric cardiac surgery using data from existing double-arm studies.The administration of rFVII does not provide any added advantage forbleeding control among pediatric patients of cardiac surgery. However, it increased the rate of reexploration among the intervention arm Addationaly, Man-Chiu Poon et.al concluded that despite the results of GTR, there is a need for more data to support the efficacy and safety of rFVIIa in patients without platelet antibodies, without refractoriness to platelets and in cases when platelets are not readily available. This study aimed to demonstrate the clinical pattern of Glanzemnn thrombathenia in children attending Assiut University Children Hospital

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