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Processed Electroencephalography-guided General Anesthesia and Outcomes in Major Abdominal Surgery
Sponsor: Assiut University
Summary
This study aims to evaluate whether the reduction in the amount of intraoperative norepinephrine required to prevent hypotension, facilitated by processed electroencephalography (pEEG) -guided general anesthesia, will lead to a decrease in postoperative complications, particularly acute kidney injury (AKI).
Official title: Impact of Reduced Intraoperative Norepinephrine Requirements Via Processed Electroencephalography-Guided General Anesthesia on Patient Outcomes After Major Abdominal Surgeries
Key Details
Gender
All
Age Range
18 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
162
Start Date
2025-02-01
Completion Date
2027-01-01
Last Updated
2025-02-04
Healthy Volunteers
No
Conditions
Interventions
Processed electroencephalography (pEEG) Guided General Anesthesia
Processed electroencephalography (pEEG) can guide the optimization of anesthesia depth, potentially preventing overly deep anesthesia and, in turn, reducing the incidence of IOH and the need for vasopressors . Depth of anesthesia will be managed based on pEEG monitoring using Entropy with a target range of 40-60.
Non-pEEG-Guided General Anesthesia (with blinded pEEG monitoring)
Depth of anesthesia will be managed based on clinical judgment, informed by clinical perception and vital signs.
Locations (1)
Assiut University Hospitals
Asyut, Egypt