Clinical Research Directory

Inclusion Criteria: 1. Chinese Han patients aged 40 years or older 2. clinical diagnosis of age-related cataracts; 3. underwent FLACS with insertion of a posterior chamber IOL for the first eye. Exclusion Criteria: 1. coexisting macular pathologies such as epiretinal membrane, macular hole or edema, or age-related macular degeneration. Patients with OCT scans of poor quality were excluded; 2. preoperative flare of more than 15ph/ms11, ECD\<2000cells/mm2 or any other corneal pathologies; 3. coexisting serious ocular diseases including uveitis, uncontrolled glaucoma, optic atrophy , amblyopia, retinopathies, or inflammatory pathology of the eye; 4. history of intraocular trauma, surgery, or retinal laser procedures; 5. usage of systemic or topical steroids or NSAIDs within one month prior to surgery; 6. patients with diabetes or any other systemic diseases that might confound the results or increase the risk for postoperative inflammation; 7. intraoperative complications such as capsule tear, hyphema, vitreous loss, iris manipulation, or miosis after laser pre treatment requiring intracameral injection of epinephrine; 8. ocular conditions contraindicating FLACS including poorly dilated pupils (\<5.0mm), narrow palpebral fissure, small hyperopic eyes with steep cornea (difficult to achieve suction), severe conjunctival chalasis, nystagmus, or lack of cooperation; 9. potentially pregnant women; 10. known sensitivity to concomitant medications used during perioperative period, participation in other clinical trial during the time of visit, or poor cooperation in diagnostic tests or non-compliance at follow-up.