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NOT YET RECRUITING
NCT06754969
NA

Does RPNI Reduce Incidence of Neuroma Formation Following Sural Nerve Biopsy

Sponsor: University of British Columbia

View on ClinicalTrials.gov

Summary

The purpose of our project is to determine if incorporating preventative surgical techniques such as regenerative peripheral nerve interfaces (RPNI) into sural nerve biopsy can reduce the incidence of symptomatic neuroma formation. Findings from this study will inform best practice guidelines and can dramatically impact patient care, improve patient quality of life, and reduce the number of required repeat operations.

Official title: Does RPNI Reduce Incidence of Neuroma Formation Following Sural Nerve Biopsy: a Pilot Study

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

20

Start Date

2025-03

Completion Date

2026-12

Last Updated

2025-01-01

Healthy Volunteers

No

Interventions

PROCEDURE

Peripheral Nerve Regenerative Interface (RPNI) and Nerve/Muscle Biopsy

RPNI is a surgical technique which wraps denervated muscle targets around severed nerve ends.

PROCEDURE

Biopsy Alone

Sural nerve and muscle biopsy performed in the standard fashion.

Locations (3)

UBC Division of Plastic Surgery

Vancouver, British Columbia, Canada

Vancouver General Hospital

Vancouver, British Columbia, Canada

Saint Pauls Hospital

Vancouver, British Columbia, Canada