Clinical Research Directory

Inclusion Criteria: * Informed consent signed by the subject * Age ≥ 60 years * Edentulous and wearing sufficient complete maxillary and mandibular dentures or ones that can be rendered sufficient via a reline and/or renewal of the prosthetic teeth * Healed edentulous mandible (minimum 6-8 weeks since last extraction in the anterior zone (4-4) and one year in the posterior zone (5-8)) * Physical status ASA1 and ASA2 Exclusion Criteria: * Contraindications to the medical devices used, e.g. known hypersensitivity or allergy * Vulnerable subjects * Enrollment of the investigator, his/her family members, employees and other dependent persons * Known or suspected non-compliance, drug or alcohol abuse * Inability to perform adequate oral hygiene * Inability to follow the procedures of the investigation, e.g. due to language problems, psychological disorders, dementia, Parkinson etc. of the subject (Dementia: clock-drawing test score ≤ 5) * Surgical risk factors such as, but not limited to, uncontrolled diabetes, immunosuppression, radiation, chemotherapy, or antiresorptive medication (ex. Bisphosphonates) * Heavy smoking habit: \>20 cig/d * Reported severe bruxism or clenching habits, clinically present oro-facial pain * Depression: Geriatric Depression Scale \> 9 * Xerostomia: SSFR ≤ 0.7ml/min * Ridge dimensions \<6 mm (width) by 10 mm (height) in the canine or midline area * Ridge defects requiring bone augmentation procedures