Clinical Research Directory
Browse clinical research sites, groups, and studies.
Reinforced Pancreaticojejunostomy With or Without glubran2
Sponsor: Minia University
Summary
Pancreatic fistula is one of the most serious complication after pancreatoduodenectomy. To reduce pancreatic fistula, many authors recommend different techniques in pancreatojejunostomy. The purpose of this study is to determine which is the best method in preventing pancreatic fistula by enforce pancreaticojejunostomy with tissue glue .
Official title: Impact of Reinforced Pancreaticojejunostomy With or Without Tissue Adhesive Glue Modified Cyanoacrylate (Glubran 2) Following Pancreaticoduodenectomy, Randomized Controlled Clinical Trial.
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2025-01-15
Completion Date
2026-05-15
Last Updated
2026-03-16
Healthy Volunteers
No
Interventions
Reinforced pancreaticojejunostomy with tissue adhesive glue modified cyanoacrylate (glubran 2)
pancreaticojejunostomy was done with application of glubran 2: The blister pack was opened, and the sterile single-dose vial was released directly onto the operating table in a sterile environment, Draw the Glubran 2 out of the single-dose vial using a sterile syringe then put the syringe into applicator Glubran 2 was applied into anastomosis by applicator in spraying manner . Whenever possible, the area to be treated should be cleaned before application. When applied in such a minimal amount, once it had polymerized, Glubran 2 formed a thin adhesive layer. It was therefore essential not to apply more than one drop in the same point. A second layer of Glubran 2 may not be applied until the first had polymerized. Any excess product was removed using a dry swab within 5-6 seconds after application. Glubran 2 was not touched after application until the polymerization reaction is complete, as it may detach or not produce the desired effect.
Pancreaticojejunostomy without tissue adhesive glue modified cyanoacrylate (glubran 2)
Pancreaticojejunostomy without tissue adhesive glue modified cyanoacrylate (glubran 2)
Locations (1)
Liver and GIT hospital / Minia university
Minya, Egypt