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Shock Wave Versus Low Level Laser on Chronic Venous Ulcer
Sponsor: Beni-Suef University
Summary
To find out the difference in the effect of shock wave therapy and low level laser therapy on venous ulcer patient As regards the following outcomes; 1. medical state of patient no ( diabetes, hypertension,obesity,cancer , rheumatoid) 2. The degree of ulcer 3. recurrence of ulcer 4. The degree of pain and disabilities 5. inflammatory marker
Official title: Effect of Extra Corporeal Shock Wave Versus Low Level Laser on Chronic Venous Ulcer Healing
Key Details
Gender
All
Age Range
45 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
45
Start Date
2025-01-01
Completion Date
2025-07-01
Last Updated
2025-01-03
Healthy Volunteers
No
Conditions
Interventions
extra corporeal shock wave therapy (ESWT )
Using wound area measurements and histological/immunohistochemical analysis of wound biopsies, we show ESWT enhanced healing of chronic ulcers associated with improved wound angiogenesis ), significantly decreased-positive macrophages per biopsy area and generally increased macrophage activity ,this activity prevent bacterial infection which delay healing
Low Level Laser Therapy
Low-level laser therapy (LLLT) has been used as an adjuvant to conventional therapy with promising results,improve healing by delivering nutrient substances , especially in patients with acute and bloody ulcers. Positive effects include acceleration of tissue repair, increased formation of granulation tissue, wound contraction, inflammation modulation, and pain reduction The biochemical effects of LLLT are associated with the release of preformed substances (histamine, serotonin, and bradykinin), which stimulate the production of ATP and inhibit the production of prostaglandins.
conservative treatments
( compression pandaging, lifestyle changes, physical activities)