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Post Extraction Changes After Alveolar Socket Preservation Using Autogenous Dentin Graft (ADG) Combined With Either Albumin Platelet-rich Fibrin (ALB-PRF) or Standard Platelet-rich Fibrin (PRF).
Sponsor: Kafrelsheikh University
Summary
The study focuses on the impact of tooth loss on alveolar bone, which shrinks significantly within the first three months. To prevent this, strategies like alveolar ridge preservation are used. Autogenous dentin, taken from the patient, supports healing and bone regrowth. Platelet-rich fibrin (PRF), made from the patient's blood, enhances healing and bone density by releasing growth factors. A new technique combining L-PRF with albumin creates a stable healing membrane that provides a steady release of growth factors. Overall, these methods improve recovery after tooth extractions and prepare sites for future dental work.
Official title: Comparison of Autogenous Dentin Graft With Albumin Platelet Rich Fibrin Versus Autogenous Dentin Graft With Platelet Rich Fibrin in Alveolar Socket Preservation: A Randomized Controlled Clinical Trial.
Key Details
Gender
All
Age Range
18 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2025-06-01
Completion Date
2026-08-30
Last Updated
2025-07-10
Healthy Volunteers
No
Conditions
Interventions
empty socket
Patients will be left socket empty without any graft materials for spontaneous healing process after tooth extraction
Autogenous Dentin Graft with Platelet Rich Fibrin
Patients will be inserting autogenous dentin graft and platelet rich fibrin in the socket after extraction.
Autogenous Dentin Graft with Albumin Platelet Rich Fibrin
Patients will be inserting autogenous dentin graft and Albumin Platelet Rich Fibrin in the socket after extraction.
Locations (1)
Kaferelsheikh University
Kafr ash Shaykh, Kafrelsheikh, Egypt