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Evaluation of Different Serum Cartilage Biomarkers in the Acute Response to Walking and Cycling in Healthy Male Subjects
Sponsor: Kocaeli University
Summary
The effect of physical activity on serum cartilage biomarkers is largely unknown. This study is critical to increase our knowledge of the physiological cartilage response to activities of daily living and dynamic tasks by focusing on healthy recreationally active individuals, thus improving our understanding of the complex relationship between cartilage health and the loading that occurs during different types of loading.
Key Details
Gender
MALE
Age Range
20 Years - 35 Years
Study Type
EXPANDED_ACCESS
Enrollment
Not specified
Start Date
Not specified
Completion Date
Not specified
Last Updated
2026-06-10
Healthy Volunteers
Yes
Conditions
Interventions
Walking
Participants will perform 30 minutes of walking and cycling exercises. During the cycling and walking exercises, heart rate will be calculated using the Karvonen formula based on heart rate reserve. HRmax (maximum heart rate)=220-age HRR (%)(heart rate reserve)= (HR-HRrest)/(HRmax-HRrest)\*100 Blood samples will be collected from participants before starting the exercise, at the end of the 30-minute exercise session, and twice more at 30-minute intervals. The same participants will perform the cycling exercise half an hour later, and the same procedures will be applied.
Cycling
Cycling
Locations (2)
Kocaeli University Faculty of Medicine Hospital
Kocaeli, Turkey (Türkiye)
Sakarya University Applied Sciences Physiotherapy and Rehabilitation Application and Research Center
Sakarya, Turkey (Türkiye)