Clinical Research Directory

Inclusion Criteria: * Male or female participant of any race or ethnicity between 18-70 years of age (inclusive) at the time of informed consent * BMI between 25-35 kg/m2 * Non-smoker * Willing to consume 3 eggs per day for one dietary period of 4 weeks * Willing to avoid eggs during the rest of the study including washout period breaks except for eggs that are provided * Willing to fast before the baseline and dietary period lab visits * Willing to provide a 24-hr prior day food record at the dietary period lab visits * Willing to provide or collect biological specimen samples at the baseline and dietary period lab visits * Willing to follow the study protocol including maintaining usual lifestyle during the entire study Exclusion Criteria: * Male or female \< 18 years or \> 70 years of age at the time of consent * BMI \< 25 kg/m2; or BMI \> 35 kg/m2 * Pregnant or planning to become pregnant during the course of the study; currently breastfeeding or postpartum \< 6 months * Use of hormone therapy including birth control pills * Follows a vegan diet * Current smoker (any form of nicotine, e-cigarettes, etc) * Use of recreational drugs (may affect metabolic pathway for choline) * Presence of chronic illnesses, e.g., heart disease, diabetes, cancer, celiac disease, inflammatory bowel disease (Crohn's disease and ulcerative colitis), gastrointestinal liver or kidney diseases or alcoholism * Diagnosis of trimethylaminuria (genetic disorder affecting choline use in body) * Use of antibiotics in the last 2 months * Use of prebiotics, probiotics or dietary fiber (i.e., Metamucil) supplements in the last 2 months * Have allergies to eggs or any anaphylactic food allergies * Have a schedule or lifestyle patterns incompatible with the study protocol