Inclusion Criteria:
* Oligomenorrheic females (Menstrual cycle duration between 36-45 days), aged between 25 and 35 years and with a Body Mass Index (BMI) between 20 to 29.9 kg/m2.
* Subjects with maximum pain intensity ≥40 mm on a 100 mm VAS for at least 2 menstrual cycles before participating in the study.
* Subjects with normal thyroid profile.
* Subjects who are non-smokers and non-alcohol user.
* Subject understands the study procedures and provides signed informed consent to participate in the study.
* Females of childbearing potential who are sexually active must agree to use adequate non-hormonal contraception during the study.
* Normal vital signs, including electrocardiogram (ECG) and laboratory evaluations (including clinical chemistry, hematology, and complete urinalysis) within the reference range for the testing laboratory or the results are deemed not clinically significant for inclusion into this study by the investigator.
Exclusion Criteria:
* History of any gynaecological disorders which effects the study indication.
* History of cerebrovascular disease, thrombo-embolic disorders, heart attack, or angina at any time or thrombophlebitis within the last 5 years, on anti-coagulant or anti-platelet drugs on a daily basis for any conditions.
* Subjects who had any hormonal therapy, metformin or any other herbal products in the past 3 months.
* Hypothyroidism, hyperthyroidism, hyperprolactinemia, Cushing's syndrome and congenital adrenal hyperplasia, following a special diet for the past 3 months, taking drugs affecting insulin sensitivity or lipid and hormonal profiles, including glucocorticoids, ovulation-stimulating drugs, anti-obesity, anti-diabetes, anti-hypertensive, anti-estrogenic, anti-androgenic during the last 3 months (except the usual drugs of the subjects).
* Active gall bladder disease, gynaecological or breast surgery in the last 6 months.
* Subjects underwent hysterectomy.
* History of breast, endometrial, other gynaecological cancer at any time or other cancer within the last 5 years.
* Pregnant and lactating mothers.
* History of hypersensitivity reactions attributed to investigational product (IP) or its components or related products.
* History of positive hepatitis, including Hepatitis B surface antigen or Hepatitis C virus (HCV) antibodies or subjects with human immunodeficiency virus (HIV) and /or syphilis.
* History of clinically significant illness or any other medical disorder that may interfere with subject treatment, assessment or compliance with the protocol.
* Participated in a clinical study with an investigational drug or biologic within the last 60 days.
* Any condition that in opinion of the investigator, does not justify the subjects' participation in the study.
* Subjects who are being treated for liver cancer or cirrhosis, chronic renal failure, congestive heart failure.
* Subjects with a systemic disease including tuberculosis, leucosis, collagenosis, multiple sclerosis or other autoimmune diseases.
* Subjects with a high blood pressure at screening (systolic blood pressure ≥140 mmHg or diastolic blood pressure ≥ 90 mmHg).
* Consumption of recreational drugs (such as cocaine, methamphetamine, marijuana, etc.) or psychiatric drug users.
