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Nebulized Dexmedetomidine for Post-Anesthesia Delirium in Preschool Children
Sponsor: Udayana University
Summary
Analyzing the effectiveness of nebulized dexmedetomidine 2 mcg/kg in reducing the incidence of post-anesthesia delirium in preschool children undergoing elective surgery with sevoflurane inhalation general anesthesia. Researchers will compare nebulized Dexmedetomidine to a placebo (a look-alike substance that contains no drug) to see if the drug can reduce post anesthesia delirium incidence.
Official title: Nebulized Dexmedetomidine to Reduce Post-Anesthesia Delirium of Sevoflurane in Preschool Children Undergoing Elective Surgery
Key Details
Gender
All
Age Range
2 Years - 6 Years
Study Type
INTERVENTIONAL
Enrollment
72
Start Date
2024-12-13
Completion Date
2025-02-13
Last Updated
2025-01-22
Healthy Volunteers
Yes
Interventions
Nebulized Dexmedetomidine for Post-Anesthesia Delirium in Preschool Children
Nebulization with the anesthetic drug dexmedetomidine at a dose of 2 mcg/kg body weight, diluted to 3 ml with 0.9% normal saline, administered before the induction of anesthesia in the reception area. After the anesthesia, primary data collection is conducted by recovery room staff who are blinded to the treatment and control groups. Data includes scores or levels of post-anesthesia delirium or agitation assessed using the PAED score at 15, 30, 60, and 120 minutes post-surgery in the recovery room
Nebulized 0.9% Normal Saline
Nebulization with normal saline 0.9% 3 ml, administered before the induction of anesthesia in the reception area. After the anesthesia, primary data collection is conducted by recovery room staff who are blinded to the treatment and control groups. Data includes scores or levels of post-anesthesia delirium or agitation assessed using the PAED score at 15, 30, 60, and 120 minutes post-surgery in the recovery room
Locations (1)
Anesthesiology and Intensive Therapy Udayana University
Denpasar, Bali, Indonesia