Clinical Research Directory
Browse clinical research sites, groups, and studies.
Is Negativity of Autoantibodies a Marker of Severity in Auto-immune Hepatitis?
Sponsor: Centre Hospitalier Universitaire de la Guadeloupe
Summary
Evaluate the proportion of seronegative auto-immune hepatitis and a possible relationship with the severity of the disease. Criteria of severity will be defined by corticodependance, corticoresistance and a severe form of the disease at diagnosis (cirrhosis or fulminant hepatitis). In case of predominant seronegative forms, other auto-antibodies related to this auto-immue hepatitis will be searched.
Official title: Is Negativity of Autoantibodies a Marker of Severity in Auto-immune Hepatitis
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
100
Start Date
2022-07-01
Completion Date
2026-12
Last Updated
2025-01-07
Healthy Volunteers
No
Conditions
Interventions
blood sampling
For the study, a blood sample will be collected from the patient in order to do build up a serological library which will allow the search for rare autoAb whose interest has been demonstrated as prognostic factors of the disease.
Locations (2)
Hospital of Saint-Antoine
Paris, France, France
CHU de Pointe-à Pitre
Pointe à Pitre, Guadeloupe, France