Clinical Research Directory

Inclusion Criteria: 1. Meet mild to moderate rosacea, acne diagnostic criteria; Meet the diagnostic criteria for melasma; 2. Over 18 years of age; 3. Be able to follow the treatment rules of the study and be followed for 8 weeks; 4. Informed consent; 5There were no significant cardiac, liver, kidney, gastrointestinal, neurological, psychiatric, or metabolic disorders 6.No medication was used within 1 month Exclusion Criteria: 1. Currently pregnant, planning to become pregnant or breastfeeding; 2. Documented hypersensitivity to any active ingredient or excipient included in the study drug, or a history of adverse reactions to cosmetic products; 3. Participate in other clinical studies within 3 months before the start of the study; 4. Frequent use of Chinese medicine, sleeping pills, sedatives, anti-anxiety drugs or potentially addictive substances; 5. Present with concomitant skin conditions that may confuse the clinical assessment of rosacea, melasma, seborrheic dermatitis or pose a risk to participants, or have a history of severe skin conditions; 6. Normal use of relevant treatment (including intense pulsed light, pulsed fuel laser, oral and topical tranexamic acid, oral tetracycline antibiotics, oral compound glycyrrhizin and other anti-inflammatory drugs) 7. Patients with incomplete observation data, incomplete course of treatment and inability to take drugs as prescribed by doctors were removed