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The Effectiveness of Allogenic Mesenchymal Stem Cells Therapy on Hair Regrowth in Androgenetic Alopecia.
Sponsor: National Institute of Blood and Marrow Transplant (NIBMT), Pakistan
Summary
The goal of this study is to learn if mesenchymal stem cell therapy (treatment group) can effectively treat adrogenic alopecia or male-pattern baldness, when compared to normal saline (given to placebo group). It will also assess the differences in patient satisfaction. The main focus will be to: 1. Compare the average hair regenerative effect of mesenchymal stem cells versus Placebo, in treatment of androgenetic alopecia. 2. To determine and compare the investigators assessment and patient satisfaction in both groups. Patients in treatment group will receive single session of MSC therapy injected in the scalp and placebo group will receive 0.9% saline solution. The participants will be followed for 12 weeks. The hair density and thickness will be mesured along with clinicians assessment and participant's satisfaction level.
Official title: The Effectiveness of Allogenic Mesenchymal Stem Cells Therapy on Hair Regrowth in Androgenetic Alopecia: a Randomized, Double-Blind, Placebo Control Trial
Key Details
Gender
MALE
Age Range
20 Years - 59 Years
Study Type
INTERVENTIONAL
Enrollment
70
Start Date
2024-12-25
Completion Date
2025-08-30
Last Updated
2025-01-08
Healthy Volunteers
No
Interventions
Mesenchymal Stem Cells
allogeneic bone marrow-derived mesenchymal stem cells therapy
0.9 % saline
0.9% Saline as placebo
Locations (2)
Department of dermatology, Pak-Emirates Military Hospital
Rawalpindi, Pakistan
National Institute of Blood and Marrow Transplant (NIBMT)
Rawalpindi, Pakistan