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An Ex-US Study to Assess Treatment Persistence With Risankizumab in Adult Participants With Psoriatic Arthritis
Sponsor: AbbVie
Summary
Psoriatic arthritis (PsA) is a type of arthritis (swelling and stiffness in the joints) that is frequently seen in trial participants who also have the skin condition psoriasis. It is caused by an overactive immune system where the body attacks healthy tissue by mistake. This study aims to describe the long term usage and effectiveness with risankizumab (RZB) relative to other advanced therapeutic options for the management of PsA in daily clinical practice. Risankizumab is an approved drug for the treatment of psoriatic arthritis. The study will not be conducted in the United States, however it will be conducted in approximately 15 countries and include at least 900 and up to 1200 participants with a 2 to1 ratio of participant allocation between participants receiving risankizumab and participants receiving other advanced therapeutic agents. The therapy is prescribed in the usual manner in accordance with the terms of the local marketing authorization and professional and reimbursement guidelines with regards to dose, population, and indication. All study visits will occur during routine clinical practice and participants will be followed for 24 months. There is expected to be no additional burden for participants in this study.
Official title: Prospective Multi-country, Real-world, Multi-arm Study of Treatment PErsistence With RISankizumab in Psoriatic Arthritis (PERIS)
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
OBSERVATIONAL
Enrollment
1200
Start Date
2025-01-31
Completion Date
2029-02
Last Updated
2026-02-17
Healthy Volunteers
No
Conditions
Locations (132)
Cer Instituto Médico /ID# 274445
Quilmes, Buenos Aires, Argentina
Instituto Medico de Alta Complejidad San Isidro S.A. /ID# 274417
San Isidro, Buenos Aires, Argentina
Instituto Médico Río Cuarto /ID# 274421
Río Cuarto, Córdoba Province, Argentina
Landesklinikum Stockerau /ID# 275618
Stockerau, Lower Austria, Austria
Medizinische Universitaet Graz /ID# 273765
Graz, Styria, Austria
Krankenhaus Der Barmherzigen Brueder Graz /ID# 273764
Graz, Styria, Austria
Rheuma-Zentrum Wien-Oberlaa GmbH /ID# 275617
Vienna, Vienna, Austria
Universite Libre de Bruxelles - Hopital Erasme /ID# 272763
Anderlecht, Brussels Capital, Belgium
Rhumaconsult Sprl /ID# 272797
Charleroi, Hainaut, Belgium
Reumacentrum Genk - Medisch Centrum Genk /ID# 272796
Genk, Limburg, Belgium
ReumaClinic /ID# 272782
Genk, Limburg, Belgium
OLV Ziekenhuis Aalst /ID# 274456
Aalst, Oost-Vlaanderen, Belgium
UZ Leuven /ID# 272781
Leuven, Vlaams-Brabant, Belgium
CHU de Liege /ID# 272784
Liège, Belgium
Diagnostic Consultative Centre (Dcc) - Foкus 5 /ID# 275952
Sofiya, Sofia, Bulgaria
Military Hospital - Pleven /ID# 276054
Pleven, Bulgaria
Medical Center Epiona /ID# 276037
Plovdiv, Bulgaria
University Multiprofile Hospital For Active Treatment Pulmed /ID# 276157
Plovdiv, Bulgaria
Dr. Tsvetanka Petranova ELIMED - 2 /ID# 276158
Sofia, Bulgaria
Medical Center Academy /ID# 276041
Sofia, Bulgaria
AIPSMPR -d-r Gerganov /ID# 275953
Varna, Bulgaria
MAPO revma /ID# 272409
Ostrava, Ostrava-mesto, Czechia
Fakultni Nemocnice Plzen /ID# 276061
Pilsen, Praha 17, Czechia
Centre Hospitalier Universitaire de Nice - Hopital Pasteur /ID# 274923
Nice, Alpes-Maritimes, France
Infirmerie Protestante De Lyon /ID# 274922
Caluire-et-Cuire, Auvergne-Rhône-Alpes, France
Centre Hospitalier Universitaire Gabriel-Montpied /ID# 275399
Clermont-Ferrand, Auvergne-Rhône-Alpes, France
Chu Grenoble - Hôpital Sud /ID# 275200
Échirolles, Auvergne-Rhône-Alpes, France
Centre Hospitalier Regional Universitaire de Besancon - Hopital Jean Minjoz /ID# 277881
Besançon, Doubs, France
Centre Hospitalier D'Arras /ID# 275192
Arras, Hauts-de-France, France
CHU de Lille - Hôpital Salengro /ID# 274980
Lille, Hauts-de-France, France
Chu Montpellier /ID# 274925
Montpellier, Herault, France
Chru De Rennes - Hôpital Sud /ID# 277115
Rennes, Ille-et-Vilaine, France
Centre Hospitalier Régional Universitaire De Tours - Hôpital Trousseau /ID# 275397
Chambray-lès-Tours, Indre-et-Loire, France
Clinique François Chénieux /ID# 276516
Limoges, Limousin, France
CHU Limoges - Dupuytren 2 /ID# 274918
Limoges, Nouvelle-Aquitaine, France
Pôle Santé du Pont de Chaume /ID# 275608
Montauban, Occitanie, France
Centre Hospitalier Boulogne-Sur-Mer /ID# 277269
Boulogne-sur-Mer, Pas-de-Calais, France
Centre Hospitalier Universitaire de Nantes, Hotel Dieu -HME /ID# 275396
Nantes, Pays de la Loire Region, France
Hôpital Privé De Provence /ID# 275797
Aix-en-Provence, Provence-Alpes-Côte d'Azur Region, France
Centre Hospitalier De Cannes - Hôpital De Cannes /ID# 275193
Cannes, Provence-Alpes-Côte d'Azur Region, France
Centre Hospitalier Universitaire de Rouen (CHU)- Hopital Charles Nicolle /ID# 275366
Rouen, Seine-Maritime, France
Cabinet libéral du Dr PAUPIERE /ID# 275401
Péronne, Somme, France
Henri Mondor Hospital /ID# 275360
Créteil, Val-de-Marne, France
CH de Cahors /ID# 275092
Cahors, France
Centre Hospitalier Régional d'Orléans - Hôpital de la Source /ID# 275377
Orléans, France
AP-HP - Groupe Hospitalier 10e - Hopital Lariboisiere /ID# 275182
Paris, France
Groupe Hospitalier Paris Saint-Joseph /ID# 274981
Paris, France
Centre Hospitalier de Valenciennes /ID# 276354
Valenciennes, France
Centre Hospitalier Sud Francilien /ID# 275038
Corbeil-Essonnes, Île-de-France Region, France
Hopital Pitie Salpetriere /ID# 275368
Paris, Île-de-France Region, France
Dr. Med. Thomas Marycz /ID# 280489
Amberg, Bavaria, Germany
Klinische Forschung Im Medizinischen Versorgungalltag Gbr /ID# 276208
Planegg, Bavaria, Germany
Private Practice - Dr. Dirk Wernicke /ID# 279748
Hohen Neuendorf, Brandenburg, Germany
Rheumatologisch Immunologisch /ID# 275832
Templin, Brandenburg, Germany
Deutsches Endokrinologisches Versorgungszentrum DEVZ - MVZ GdR /ID# 276484
Frankfurt am Main, Hesse, Germany
Rheumateam Lahn-Dill-Siegerland /ID# 276019
Wetzlar, Hesse, Germany
Praxis. F. Bigdeli-Wilshusen /ID# 275522
Hanover, Lower Saxony, Germany
Rheumatologie Kassel /ID# 276311
Kassel, Lower Saxony, Germany
Rheumazentrum Ratingen /ID# 278190
Ratingen, North Rhine-Westphalia, Germany
Praxis Dr. med. Florian Beyer /ID# 276233
Kaiserslautern, Rhineland-Palatinate, Germany
Krankenhaus der Barmherzigen Brüder Trier /ID# 278759
Trier, Rhineland-Palatinate, Germany
Knappschaftsklinikum Saar /ID# 279850
Püttlingen, Saarland, Germany
Rheumapraxis Dr. Prothmann /ID# 275712
Püttlingen, Saarland, Germany
Rheumapraxis Dr. Liebhaber /ID# 276235
Halle, Saxony-Anhalt, Germany
Rheumatologische Facharztpraxis /ID# 276359
Magdeburg, Saxony-Anhalt, Germany
Universitaetsklinikum Schleswig-Holstein Campus Luebeck /ID# 275711
Lübeck, Schleswig-Holstein, Germany
Private Practice - Dr. Jochen Walter /ID# 280067
Rendsburg, Schleswig-Holstein, Germany
Private Practice - Dr. Thomas Kupka /ID# 276236
Altenburg, Thuringia, Germany
Rheumapraxis Steglitz /ID# 279413
Berlin, Germany
Private Practice - Dr. Silke Zinke /ID# 279350
Berlin, Germany
MVZ Herzogin Elisabeth Hospital /ID# 275583
Braunschweig, Germany
Praxis Fiene /ID# 279363
Greifswald, Germany
Cellitinnen-Krankenhaus St. Josef /ID# 275710
Wuppertal, Germany
Olympion General Clinic /ID# 271685
Pátrai, Achaia, Greece
Athens Naval Hospital /ID# 272313
Athens, Attica, Greece
General Hospital of Athens Ippokratio /ID# 262528
Athens, Attica, Greece
General Hospital of Athens Laiko /ID# 272325
Athens, Attica, Greece
General Hospital of Athens Laiko /ID# 272410
Athens, Attica, Greece
University General Hospital Attikon /ID# 272358
Athens, Attica, Greece
Asklipieio General Hospital of Voula /ID# 272326
Voula, Attica, Greece
University General Hospital of Heraklion /ID# 271743
Heraklion, Crete, Greece
University General Hospital of Alexandroupolis /ID# 272411
Alexandroupoli, Evros, Greece
The University Hospital of Larissa /ID# 272315
Larissa, Larisa, Greece
KAT Atttica General Hospital /ID# 271741
Athens, Greece
General Hospital of Ioannina G. Hatzikosta /ID# 272327
Ioannina, Greece
Bioclinic Thessaloniki /ID# 272316
Thessaloniki, Greece
General Hospital of Thessaloniki Hippokrateio /ID# 272314
Thessaloniki, Greece
Euromedica General Clinic of Thessaloniki /ID# 272412
Thessaloniki, Greece
Euromedica General Clinic of Thessaloniki /ID# 275805
Thessaloniki, Greece
St James Hospital /ID# 260024
Dublin, Dublin, Ireland
St Vincents University Hospital /ID# 261237
Elm Park, Dublin, Ireland
University Hospital Kerry /ID# 266733
Tralee, Kerry, Ireland
Cork University Hospital /ID# 268263
Cork, Ireland
Beaumont Hospital /ID# 271961
Dublin, Ireland
Tallaght University Hospital /ID# 277000
Dublin, Ireland
Meir Medical Center /ID# 273315
Kfar Saba, Central District, Israel
The Chaim Sheba Medical Center /ID# 273313
Ramat Gan, Tel Aviv, Israel
Tel Aviv Sourasky Medical Center /ID# 273311
Tel Aviv, Tel Aviv, Israel
The Lady Davis Carmel Medical Center /ID# 273312
Haifa, Israel
Hadassah Medical Center-Hebrew University /ID# 273314
Jerusalem, Israel
Galilee Medical Center /ID# 275431
Nahariya, Israel
IRCCS Istituto Clinico Humanitas /ID# 264463
Rozzano, Lombardy, Italy
ASST Centro Specialistico Ortopedico Traumatologico Gaetano Pini-CTO /ID# 265161
Milan, Milano, Italy
IRCCS Ospedale San Raffaele /ID# 266212
Milan, Milano, Italy
Azienda Ospedaliera Universitaria Luigi Vanvitelli /ID# 266888
Naples, Napoli, Italy
Azienda Ospedaliero-Universitaria Policlinico Umberto I /ID# 265145
Rome, Roma, Italy
Azienda Ospedaliero Universitaria delle Marche /ID# 264636
Ancona, Italy
ASST degli Spedali Civili di Brescia /ID# 264699
Brescia, Italy
Universita degli Studi del Molise /ID# 265162
Campobasso, Italy
AOU Policlinico G. Rodolico - San Marco /ID# 264459
Catania, Italy
ASL 2 Abruzzo Lanciano-Vasto-Chieti /ID# 265640
Chieti, Italy
Azienda Ospedaliero Universitaria Pisana /ID# 264938
Pisa, Italy
Azienda Ospedaliera Universitaria Senese /ID# 265207
Siena, Italy
ASU FC - P.O. Universitario Santa Maria della Misericordia /ID# 264698
Udine, Italy
Indywidualna Specjalistyczna Praktyka Lekarska dr hab.n.med.Katarzyna Pawlak-Buś /ID# 276483
Poznan, Greater Poland Voivodeship, Poland
SOMED Renata Sokolik /ID# 276480
Wroclaw, Lower Silesian Voivodeship, Poland
Imam Abdulrahman Bin Faisal University /ID# 277716
Dammam, Eastern Province, Saudi Arabia
King Saud University /ID# 279463
Riyadh, Riyadh Region, Saudi Arabia
Hospital Universitario Virgen de la Victoria /ID# 264317
Málaga, Malaga, Spain
Hospital Rafael Mendez /ID# 272663
Lorca, Murcia, Spain
Hospital Xeral Cies (CHUVI) /ID# 272659
Vigo, Pontevedra, Spain
Hospital Universitario de Valme /ID# 264314
Seville, Sevilla, Spain
Hospital Universitario Virgen de las Nieves /ID# 275741
Granada, Spain
Hospital Universitario Clinico San Cecilio /ID# 272665
Granada, Spain
Hospital Juan Ramón Jiménez /ID# 272667
Huelva, Spain
Hospital Universitario de La Princesa /ID# 264073
Madrid, Spain
Hospital Universitario 12 de Octubre /ID# 272660
Madrid, Spain
Hospital Universitario La Paz /ID# 264316
Madrid, Spain
Hospital General Universitario Reina Sofía /ID# 272664
Murcia, Spain
Taipei Medical University - Shuang Ho Hospital, Ministry of Health and Welfare /ID# 274352
New Taipei City, Taiwan
Taichung Veterans General Hospital /ID# 274896
Taichung, Taiwan
National Taiwan University Hospital /ID# 280714
Taipei, Taiwan