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Supplementing Neuro-Energy to Aid Cognition
Sponsor: University of Pennsylvania
Summary
It is projected that by 2030, one in every five Americans will be of retirement age, and this demographic shift is expected to result in more people suffering from dementia. A key feature of the brain is its need for a constant supply of glucose and oxygen to meet the high energy costs of mental activity. This study aims to develop clinically practical, noninvasive imaging methods based on combined positron emission tomography and magnetic resonance imaging to assess brain energy in order to better understand how this critical component of brain health is impacted by aging.
Official title: Simultaneous PET/MR Imaging of Brain Glucose and Oxygen Metabolism to Assess Energy Deficits Related to Alzheimer's Disease and the Response to Intervention
Key Details
Gender
All
Age Range
21 Years - Any
Study Type
INTERVENTIONAL
Enrollment
17
Start Date
2026-05-01
Completion Date
2028-03-31
Last Updated
2025-10-14
Healthy Volunteers
Yes
Interventions
Ketogenic Supplement
Commercially available ketone ester drink
Placebo Drink
Placebo drink containing sunflower oil.
Locations (1)
Lawson Research Institute
London, Ontario, Canada