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NOT YET RECRUITING
NCT06768164
PHASE3

Quality of Life After Billroth II or Roux-en-Y for Gastric Cancer

Sponsor: Assistance Publique - Hôpitaux de Paris

View on ClinicalTrials.gov

Summary

The treatment of a local distal gastric cancer remains surgical before or after chemotherapy. Partial gastrectomy is recommended for distal location cancer The recommendations for restoring continuity are less evident. There are two main techniques: the Roux-En-Y (REY) requiring 2 anastomoses (gastro-jejunostomy and entero-enterostomy) and the Billroth 2 (B2) with a single anastomosis (gastro-jejunostomy). The choice remains matter of debate. There was no difference on the global health status score from the QLQ-C30 questionnaire. However, the health-related quality of life (HRQoL) was significantly improved only in the REY group between pre- and post-gastrectomy. A significant difference for endoscopic gastritis in favor of the REY group was reported. The purpose of this study is to determine which surgical technique improve the health related quality of life after distal gastrectomy.

Official title: Health-Related Quality Of Life After Partial Gastrectomy for Gastric Cancer: Comparison of Reconstruction by Billroth II or Roux-en-Y. A Randomized, Comparative, Multicentric, Single-blinded Study

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

250

Start Date

2025-06

Completion Date

2030-06

Last Updated

2025-05-14

Healthy Volunteers

No

Interventions

PROCEDURE

Billroth 2 (B2)

B2 technique requires a single anastomosis (gastro-jejunostomy) after distal gastrectomy

PROCEDURE

Roux-En-Y (REY)

REY technique requires 2 anastomoses (gastro-jejunostomy and entero-enterostomy) after distal gastrectomy

Locations (1)

Hôpital Saint-Antoine

Paris, France