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RECRUITING
NCT06772675
NA

Vancomycin Reduction Practices (VRP) in the NICU

Sponsor: Children's Hospital of Philadelphia

View on ClinicalTrials.gov

Summary

This multi-center, cluster randomized study aimed at improving implementation of vancomycin reducing practices (VRP) in neonatal intensive care units (NICUs). Sites will be recruited and randomized to receive either external facilitation or no external facilitation to assess the effect on center-level fidelity to the core components of VRP implementation. Interventions available to both study arms are directed at hospital staff and includes identification of local champions, educational outreach, unit-level audit \& feedback, and use of a clinical decision support tool.

Official title: Implementing Vancomycin Reducing Practices (VRP) in Preterm Infants

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

13

Start Date

2025-06-02

Completion Date

2027-09

Last Updated

2025-12-24

Healthy Volunteers

No

Interventions

BEHAVIORAL

External Facilitation

Designated external facilitators will conduct monthly meetings with local champions at each site. Designated facilitators will follow the developed facilitation guide, that includes content area to cover in each meeting, case scenarios as examples, and tips on how to communicate and support the internal facilitators. The goal is to enable problem-solving and support the local champion in implementing VRP with fidelity

Locations (13)

Kaiser Permanente Modesto Medical Center

Modesto, California, United States

Kaiser Permanente East Bay - Oakland Medical Center

Oakland, California, United States

Kaiser Permanente Roseville Medical Center

Roseville, California, United States

Kaiser Permanente San Francisco Medical Center

San Francisco, California, United States

Kaiser Permanente San Leandro Medical Center

San Leandro, California, United States

Kaiser Permanente Santa Clara Medical Center

Santa Clara, California, United States

Kaiser Permanente Walnut Creek Medical Center

Walnut Creek, California, United States

Medical Center of Princeton

Plainsboro, New Jersey, United States

Virtua Voorhees

Voorhees Township, New Jersey, United States

Lancaster General Hospital

Lancaster, Pennsylvania, United States

Hospital of the University of Pennsylvania

Philadelphia, Pennsylvania, United States

Pennsylvania Hospital

Philadelphia, Pennsylvania, United States

Chester County Hospital

West Chester, Pennsylvania, United States