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Effects of GLP-1RAs on Reproductive Outcomes in PCOS and Obesity
Sponsor: Peking University Third Hospital
Summary
The goal of this clinical trial is to examine whether benalutide combined with metformin and healthy lifestyle education in women with PCOS and obesity prior to fertility treatment improves live birth rate and other reproductive, maternal and perinatal outcomes compared to metformin plus healthy lifestyle education.
Official title: Effects of GLP-1 Receptor Agonists Combined with Metformin and Healthy Lifestyle Education Prior to Fertility Treatment on Reproductive Outcomes in Women with PCOS and Obesity
Key Details
Gender
FEMALE
Age Range
18 Years - 40 Years
Study Type
INTERVENTIONAL
Enrollment
392
Start Date
2025-03-01
Completion Date
2027-12-31
Last Updated
2025-01-14
Healthy Volunteers
No
Interventions
GLP-1 receptor agonist
3 months
Metformin
3 months
healthy lifestyle education
3 months
Locations (1)
Peking University Third Hospital
Beijing, Beijing Municipality, China