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RECRUITING
NCT06775431
PHASE3

Comparing Prophylactic Intravenous Pethidine and Intrathecal Pethidine in Preventing Post Spinal Shivering in Caesarean Section

Sponsor: Alexandria University

View on ClinicalTrials.gov

Summary

The goal of this clinical trial is to assess the effect of IV pethidine and intrathecal pethidine on the incidence, onset, duration, and intensity of shivering in females undergoing caesarean section. The main question it aims to answer is: which route is more efficacious in preventing shivering. Researchers will compare IV pethidine and intrathecal pethidine to see their effects on post spinal shivering, their effects on hemodynamic stability, nausea, vomiting, and sedation.

Official title: Comparison of Prophylactic Intravenous Pethidine Versus Intrathecal Pethidine in Preventing Post Spinal Shivering in Caesarean Section

Key Details

Gender

FEMALE

Age Range

20 Years - 40 Years

Study Type

INTERVENTIONAL

Enrollment

86

Start Date

2024-12-10

Completion Date

2025-03

Last Updated

2025-01-15

Healthy Volunteers

No

Conditions

Interventions

DRUG

Pethidine Hydrochloride 50 Mg/mL Solution for Injection

Pethidine will be administered intravenously in group A 0.5 mg/kg as premedication

DRUG

Pethidine Hydrochloride 50 Mg/mL Solution for Injection administered intrathecally

0.2 mg/kg pethidine in trathecally will be administered with bupivacaine 0.5% in group B

Locations (1)

El-Shatby University Hospital

Alexandria, Alexandria Governorate, Egypt