Clinical Research Directory
Browse clinical research sites, groups, and studies.
Pubertal Development in Patients with RASopathies
Sponsor: IRCCS Azienda Ospedaliero-Universitaria di Bologna
Summary
Retrospective, single-centre, non-profit, observational study on pubertal development in patients with RASopathies. Literature data shows that puberty can be delayed by about 2 years in patients with RASopathies and this has been associated with a reduced peak growth rate. To date, only a few numerically limited case series without molecular characterisation have been published. This descriptive study should improve knowledge of pubertal development and its influence on growth and final stature. The primary aims are to describe the age of onset and progression of pubertal development in the cohort of patients with RASopathies, both male and female, and to describe the influence of pubertal development on statural growth and final stature in the same cohort.
Key Details
Gender
All
Age Range
8 Years - 35 Years
Study Type
OBSERVATIONAL
Enrollment
40
Start Date
2024-07-25
Completion Date
2025-02-28
Last Updated
2025-01-15
Healthy Volunteers
No
Conditions
Locations (1)
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Bologna, Bologna, Italy