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Screening of Small Non-coding RNAs as an Auxiliary Diagnostic Biomarker for Gastric Cancer
Sponsor: Affiliated Hospital of Nantong University
Summary
Gastric cancer is one of the most common malignancies of the gastrointestinal system, especially in East Asia. A host of patients are diagnosed with GC at the late stage, leading to poor patient prognosis. Therefore, there is a strong demand to develop new biomarkers to detect this tumor early. Small non-coding RNA species include microRNA (miRNA), PIWI-interacting RNA (piRNA), small interfering RNA (siRNA), tRNA-derived small RNA (tsRNA), etc. It has been demonstrated that small non-coding RNAs are involved in gastric cancer cell proliferation, metastasis, progression and survival. Hence, it is considered as an auxiliary diagnostic biomarker for gastric cancer.
Official title: Screening of Small Non-coding RNAs as an Auxiliary Diagnostic Biomarker for Gastric Cancer and Exploring Its Correlation With Prognostic Diagnosis
Key Details
Gender
All
Age Range
18 Years - 85 Years
Study Type
OBSERVATIONAL
Enrollment
300
Start Date
2023-12-10
Completion Date
2026-11
Last Updated
2025-01-15
Healthy Volunteers
Yes
Conditions
Interventions
Analysis of relative quantitative of small non-coding RNAs
Each participant was enrolled to assess the of relative quantitative of small non-coding RNAs
Locations (1)
Affiliated Hospital of Nantong University
Nantong, Jiangsu, China