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NOT YET RECRUITING
NCT06777459
NA

Study of Nitrate-Rich Juice on Cognitive Function in Heavy Alcohol Drinkers: a Two-Stage Adaptive Design Real-World Clinical Trial

Sponsor: Peking University Sixth Hospital

View on ClinicalTrials.gov

Summary

It is known that alcohol consumption can lead to cognitive impairment and dysregulation of inflammatory responses. A preliminary randomized controlled trial conducted by our research team has suggested that nitrate may improve cognition in hospitalized patients with alcohol dependence. To further expand the population and applicability, this study aims to explore the effects of nitrate on cognition in a real-world population of heavy drinkers. The researchers have designed a two-stage clinical trial: the first stage involves the analysis of existing data, and the second stage will recruit 43-54 new participants for a 14-day dietary inorganic nitrate (nitrate-rich beetroot juice, \~750 mg NO3- /d) intervention.

Key Details

Gender

All

Age Range

Any - Any

Study Type

INTERVENTIONAL

Enrollment

43

Start Date

2025-01-15

Completion Date

2025-12-31

Last Updated

2025-01-15

Healthy Volunteers

No

Conditions

Interventions

DIETARY_SUPPLEMENT

Nitrate-rich beetroot juice

Nitrate-rich beetroot juice, \~750 mg NO3- /d