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NOT YET RECRUITING
NCT06777732
EARLY_PHASE1

The Efficacy and Safety of Keverprazan for Helicobacter Pylori Eradication

Sponsor: Nanjing First Hospital, Nanjing Medical University

View on ClinicalTrials.gov

Summary

The purpose of this study was to compare the efficacy of 14-day eradication of Helicobacter pylori with different doses of Keverprazan combined with Amoxicillin dual therapy and Keverprazan-based bismuth quadruple therapy and compare the adverse reactions, compliance, and factors affecting the efficacy of eradication schemes among different groups.

Official title: The Efficacy and Safety of Different Doses of Keverprazan Dual Therapy and Keverprazan-Based Bismuth Quadruple Therapy for Eradicating Helicobacter Pylori Infection: a Multicenter, Open, Randomized Controlled Study

Key Details

Gender

All

Age Range

18 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

672

Start Date

2025-03

Completion Date

2026-01

Last Updated

2025-01-16

Healthy Volunteers

No

Interventions

DRUG

Keverprazan

Potassium-competitive acid blocker

DRUG

Amoxicillin

Antibiotic for H. pylori eradication

DRUG

Furazolidone

Antibiotic for H. pylori eradication

DRUG

Colloidal Bismuth Pectin

Gastric mucosal protectant