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Neocortical Microarchitecture of Executive Function
Sponsor: University of Colorado, Denver
Summary
This study is being done to the determine the ability and utility of using the Neuropixels probes in the human brain. A Neuropixels probe will be inserted into and removed from the brain of awake human patients who are undergoing awake Deep Brain Stimulation (DBS) surgery.
Official title: Neocortical Microarchitecture of Executive Function Using Large-scale Intracranial Electrophysiology
Key Details
Gender
All
Age Range
45 Years - 85 Years
Study Type
INTERVENTIONAL
Enrollment
15
Start Date
2025-07-25
Completion Date
2027-12
Last Updated
2025-09-17
Healthy Volunteers
No
Conditions
Interventions
Temporary implatation of large-scale intracranial electrode.
The Neuropixels probe (imec, Leuven, Belgium) is a new high resolution multi electrode technology that uses custom 130-nm complementary metal-oxide-semiconductor fabrication with high surface area but low-impedance titanium nitride recordings to produce high site count devices with extreme electrode density in a small package.
brain electrode
Show that Neuropixels can safely and effectively record from large populations of neurons.
Locations (1)
University of Colorado
Aurora, Colorado, United States