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NOT YET RECRUITING
NCT06779032

Clinical Profile of Skin Aging Based on Dermoscopy Photoaging Scale and Glogau Scale - Study of Leucocyte Telomere Length, Biomarker P16, and Body Mass Index

Sponsor: Indonesia University

View on ClinicalTrials.gov

Summary

To determine the relationship between clinical appearance, dermoscopic examination results of photoaging profiles based on clinical examination, DPAS score and leucocyte telomere length, to analyze the relationship between BMI, waist circumference, triglycerides, and cellular senescence biomarker p16 levels with a population experiencing skin aging and having Fitzpatrick III-V skin types. The questions which is aim to be answered are: 1. What is the photoaging profile based on clinical examination results in skin aging cases? 2. What is the photoaging profile based on DPAS scores in skin aging cases? 3. What is the leucocyte telomere length profile in skin aging cases? 4. What is the relationship between leucocyte telomere length and clinical examination in skin aging cases? 5. What is the relationship between leucocyte telomere length and DPAS degree in skin aging cases? 6. What is the profile of cellular senescence p16 biomarker levels in a population that has experienced clinical skin aging with Fitzpatrick III-V skin types? 7. What is the skin aging profile based on the Glogau and DPAS scales in a population with Fitzpatrick III-V skin types? 8. Is there a relationship between the results of the cellular senescence p16 biomarker examination and clinical skin aging assessed based on the Glogau and DPAS scales in a population with Fitzpatrick III-V skin types? 9. Is there a relationship between the results of BMI, waist circumference, and triglyceride examinations with clinical skin aging assessed using the Glogau and DPAS scales with Fitzpatrick III-V skin types?

Key Details

Gender

All

Age Range

31 Years - 61 Years

Study Type

OBSERVATIONAL

Enrollment

70

Start Date

2025-02-05

Completion Date

2025-08-20

Last Updated

2025-01-16

Healthy Volunteers

Yes

Interventions

DIAGNOSTIC_TEST

blood draw

PCR method to see leucocyte telomere length

DIAGNOSTIC_TEST

blood draw

PCR method to see p16

Locations (1)

Universitas Indonesia

Jakarta, DKI Jakarta, Indonesia