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NOT YET RECRUITING
NCT06779617
NA

UMMS Sepsis Early Prediction Score (SEPSys) and RESCUE Score Combined Clinical Trial

Sponsor: University of Maryland, Baltimore

View on ClinicalTrials.gov

Summary

This study is designed to test two new risk scores - one designed to predict a patient's four-hour risk of developing sepsis and one designed to predict a patient's four-hour risk of deterioration (cardiac arrest, death, unplanned ICU transfer, or rapid response team call). The goal of this study is to improve provider awareness of a patient's risk of these two negative outcomes by providing them with new risk scores. The primary outcome will be the time from when the risk score becomes elevated to when vital signs such as heart rate or blood pressure are measured, suggesting an increased awareness.

Official title: Full Title: Sepsis Early Prediction System Score (SEPSys Score) and RESCUE Score Multi-Site, Two-Intervention, Cluster-Randomized, Factorial Stepped-Wedge Pragmatic Clinical Trial at the University of Mayland Medical System

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

150000

Start Date

2026-04-01

Completion Date

2027-06-30

Last Updated

2025-10-06

Healthy Volunteers

No

Interventions

DEVICE

SEPSys

The SEPSys Score is a clinical decision support tool for predicting the risk of developing sepsis in the next 4 hours. The SEPSys Score produces a 1-4, color-coded risk, where 4 (red) is the highest risk and 1 (green) is the lowest risk.

DEVICE

RESCUE

The RESCUE Score is a clinical decision support tool for predicting the risk of patient experiencing clinical deterioration (cardiac arrest, rapid response team call, death, or unplanned increase in care) in the next 4 hours. The RESCUE Score produces a 1-4, color-coded risk, where 4 (red) is the highest risk and 1 (green) is the lowest risk.

Locations (8)

University of Maryland Medical Center - Midtown

Baltimore, Maryland, United States

University of Maryland Medical Center

Baltimore, Maryland, United States

University of Maryland Upper Chesapeake Medical Center

Bel Air, Maryland, United States

University of Maryland Shore Medical Center

Easton, Maryland, United States

University of Maryland Baltimore Washington Medical Center

Glen Burnie, Maryland, United States

University of Maryland Charles Regional Medical Center

La Plata, Maryland, United States

University of Maryland Capital Region Medical Center

Largo, Maryland, United States

University of Maryland St. Joseph Medical Center

Towson, Maryland, United States