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UMMS Sepsis Early Prediction Score (SEPSys) and RESCUE Score Combined Clinical Trial
Sponsor: University of Maryland, Baltimore
Summary
This study is designed to test two new risk scores - one designed to predict a patient's four-hour risk of developing sepsis and one designed to predict a patient's four-hour risk of deterioration (cardiac arrest, death, unplanned ICU transfer, or rapid response team call). The goal of this study is to improve provider awareness of a patient's risk of these two negative outcomes by providing them with new risk scores. The primary outcome will be the time from when the risk score becomes elevated to when vital signs such as heart rate or blood pressure are measured, suggesting an increased awareness.
Official title: Full Title: Sepsis Early Prediction System Score (SEPSys Score) and RESCUE Score Multi-Site, Two-Intervention, Cluster-Randomized, Factorial Stepped-Wedge Pragmatic Clinical Trial at the University of Mayland Medical System
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
150000
Start Date
2026-04-01
Completion Date
2027-06-30
Last Updated
2025-10-06
Healthy Volunteers
No
Conditions
Interventions
SEPSys
The SEPSys Score is a clinical decision support tool for predicting the risk of developing sepsis in the next 4 hours. The SEPSys Score produces a 1-4, color-coded risk, where 4 (red) is the highest risk and 1 (green) is the lowest risk.
RESCUE
The RESCUE Score is a clinical decision support tool for predicting the risk of patient experiencing clinical deterioration (cardiac arrest, rapid response team call, death, or unplanned increase in care) in the next 4 hours. The RESCUE Score produces a 1-4, color-coded risk, where 4 (red) is the highest risk and 1 (green) is the lowest risk.
Locations (8)
University of Maryland Medical Center - Midtown
Baltimore, Maryland, United States
University of Maryland Medical Center
Baltimore, Maryland, United States
University of Maryland Upper Chesapeake Medical Center
Bel Air, Maryland, United States
University of Maryland Shore Medical Center
Easton, Maryland, United States
University of Maryland Baltimore Washington Medical Center
Glen Burnie, Maryland, United States
University of Maryland Charles Regional Medical Center
La Plata, Maryland, United States
University of Maryland Capital Region Medical Center
Largo, Maryland, United States
University of Maryland St. Joseph Medical Center
Towson, Maryland, United States