Clinical Research Directory
Browse clinical research sites, groups, and studies.
A Study to Learn How Avacincaptad Pegol (Izervay™) is Used in Clinical Practice in People Who Have Geographic Atrophy
Sponsor: Astellas Pharma Global Development, Inc.
Summary
This study is for people who have geographic atrophy due to age-related macular degeneration (AMD). AMD happens when the macula, the light-sensitive layer at the back of the eye called the retina, becomes damaged and causes a person's central vision to worsen. Geographic atrophy is an advanced form of AMD where cells in the retina waste away and die. Over time this can lead to permanent loss of vision. Avacincaptad pegol can help slow down the worsening or progression of geographic atrophy. Avacincaptad pegol is a treatment approved in the US to treat geographic atrophy. This study is about collecting information on how people with geographic atrophy are treated in routine clinical practice. This includes recording any medical problems from avacincaptad pegol. This is known as an observational study. Information will be collected from the peoples' medical records during and after treatment. The people in this study will have geographic atrophy in 1 or both eyes and they and their doctor has decided they will be treated with avacincaptad pegol. The individual's doctor decides on treatment, not the study sponsor (Astellas). People that want to take part in the study will have eye examinations that they would usually have as part of their routine care. People will also be asked to complete surveys about their eye health. These surveys will occur when treatment starts and then every 6 months for the first 2 years. After 2 years the surveys will happen once a year. The people on the study can take part if their doctor provides treatment with avacincaptad pegol and they want to continue with the study. The people on the study can take part for up to 3 years or up to 5 years, depending on when they start the study.
Official title: A Non-interventional, Observational Study to Evaluate Treatment Patterns and Safety of Avacincaptad Pegol (ACP/IZERVAY™) in Routine Clinical Practice in Patients With Geographic Atrophy Secondary to Age-related Macular Degeneration
Key Details
Gender
All
Age Range
Any - Any
Study Type
OBSERVATIONAL
Enrollment
1000
Start Date
2025-01-22
Completion Date
2030-01-31
Last Updated
2026-04-09
Healthy Volunteers
No
Conditions
Interventions
Avacincaptad pegol (ACP)
intravitreal injection
Locations (65)
Phoenix Retina Clinical Trials, LLC
Phoenix, Arizona, United States
Retinal Consultants of AZ
Phoenix, Arizona, United States
Retina Macula Institute of Arizona
Scottsdale, Arizona, United States
The Retina Partners
Encino, California, United States
Harvard Eye Associates
Laguna Hills, California, United States
University of California Irvine Medical Center
Orange, California, United States
Retina Consultants of Southern CA
Redlands, California, United States
Retinal Consultants Medical Group Inc
Sacramento, California, United States
Retina Macula Institute
Torrance, California, United States
Rocky Mountain Lions Eye Institute
Aurora, Colorado, United States
Retina Consultants of Southern Colorado
Colorado Springs, Colorado, United States
Colorado Retina Associates, PLLC
Lakewood, Colorado, United States
Coastal Eye Surgeons
Greenwich, Connecticut, United States
Florida Eye Clinic
Altamonte Springs, Florida, United States
Advanced Retina Institute
Bonita Springs, Florida, United States
University of Miami
Coral Gables, Florida, United States
Retina Care Specialists
Palm Beach Gardens, Florida, United States
Eye Physicians of Pinellas PA dba Eye Institute of West Florida
Tampa, Florida, United States
Retina Specialists of Tampa
Wesley Chapel, Florida, United States
Southeast Retina Center, P.C.
Augusta, Georgia, United States
University Retina and Macula Associates, P.C.
Oak Forest, Illinois, United States
Illinois Retina Associates
Oak Park, Illinois, United States
Illinois Eye Center
Peoria, Illinois, United States
Wolfe Eye Clinic
West Des Moines, Iowa, United States
Cumberland Valley Retina Consultants,P.C.
Hagerstown, Maryland, United States
Retina Specialists
Towson, Maryland, United States
Retina Associates of Michigan
Grand Blanc, Michigan, United States
Retina Consultants of Minnesota PLLC
Saint Louis Park, Minnesota, United States
Mississippi Retina Associates
Madison, Mississippi, United States
Brown Family Retina PLLC
Olive Branch, Mississippi, United States
Deep Blue Retina Clinical Research
Southaven, Mississippi, United States
Sierra Eye Associates
Reno, Nevada, United States
Eye Associates of North Jersey PA
Dover, New Jersey, United States
NJ Retina
Edison, New Jersey, United States
NJ Retina
Lakewood, New Jersey, United States
Monmouth Retina Consultants
Little Silver, New Jersey, United States
NJ Retina
Toms River, New Jersey, United States
SightMD
Brentwood, New York, United States
Retina-Vitreous Surgeons of Central NY
Liverpool, New York, United States
NY Retina Ophthalmology PLLC
Massapequa, New York, United States
Retina Associates of New York
New York, New York, United States
Long Island Vitreoretinal Consultants
Scarsdale, New York, United States
Vitreoretinal Consultants
Shirley, New York, United States
North Carolina Retina Associates
Cary, North Carolina, United States
North Carolina Retina Associates
Wake Forest, North Carolina, United States
The Ohio State University
Columbus, Ohio, United States
CEI Physicians PSC, LLC dba
Dayton, Ohio, United States
Verum Research, LLC
Eugene, Oregon, United States
Erie Retina Research
Erie, Pennsylvania, United States
Southeastern Retina Associates, P.C.
Knoxville, Tennessee, United States
Southeastern Retina Associates, P.C.
Knoxville, Tennessee, United States
Mid South Retina Associates
Memphis, Tennessee, United States
Tennessee Retina, PC
Nashville, Tennessee, United States
Retina Research Institute of Texas
Abilene, Texas, United States
Retina & Vitreous of Texas
Bellaire, Texas, United States
Retina of North Texas
Dallas, Texas, United States
Valley Retina Institute
McAllen, Texas, United States
Medical Center Ophthalmology Associates
San Antonio, Texas, United States
Retina Associates Of South Texas, Pa
San Antonio, Texas, United States
Retina Associates of Utah, P.C.
Murray, Utah, United States
Salt Lake Retina
Salt Lake City, Utah, United States
The Retina Group of Washington
Fairfax, Virginia, United States
Piedmont Eye Center, Inc.
Lynchburg, Virginia, United States
Virginia Retina Center
Warrenton, Virginia, United States
Retina & Vitreous Consultants of Wisconsin
Milwaukee, Wisconsin, United States