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Dynamic Cardio-vascular, Cerebro-vascular and Cortical Interaction in Healthy Adult Subjects
Sponsor: IRCCS Policlinico S. Donato
Summary
IDEALE aims to assess the status of autonomic function, cerebral autoregulation (CA) and cortical activity in healthy subjects and correlate these functions with the psychological dimension of the subjects. To this end, parameters of cardiac, cortical, vascular and cerebrovascular variability derived from electrocardiographic, electroencephalographic, respiratory movement, blood pressure, transcranial Doppler signals will be acquired and analysed for each healthy volunteer (TCD) and Laser-Doppler transcutaneous, during a phase of clinostatism (REST) and one of active orthostatism (STAND). In addition, volunteers will be submitted to psychometric tests (Chieti Affective Action Videos, CAAV) to assess the presence of depressive symptoms.
Official title: Dynamic Cardio-, Cerebro-vascular and Cortical Interaction in Healthy Adult Subjects
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
50
Start Date
2024-10-03
Completion Date
2027-10-03
Last Updated
2025-03-28
Healthy Volunteers
Yes
Conditions
Interventions
Active standing
a session at resting state in supine position, a session during autonomic challenge obtained via active standing evoking reflex sympathetic activation, and a session of emotional elicitation via the administration of videos
Locations (1)
IRCCS Policlinico San Donato
San Donato Milanese, Milano, Italy