Clinical Research Directory

Inclusion Criteria: * For the High school students' group: All students aged 13 years and older, enrolled at the selected Mtshabezi and Matopo High Schools in the Gwanda and Matobo Rural Districts during the five-year period of the project are eligible to participate in the study. Ability to understand and respond to questions on the Youth Risk Behavior Scree questionnaire and PHQ-9 scale. Relevant history of HPV vaccine administration. Ability to obtain parental/guardian consent for participation. \- For the women group: All women and young female adults thirteen to forty-five years old and requesting health services for prenatal, post-partum, family planning and other care during the five-year project period are eligible to participate. Must not have received Hep B and HPV vaccine in the past and have no known contraindications to either of these two vaccines. Are able to understand and respond to the PHQ-9 and Edinburgh Postnatal Depression scales. Must have a valid consent for participation in the study. Exclusion Criteria: * males who are not enrolled in these participating High Schools. * children below the age of thirteen who are not enrolled in high schools and are not seeking prenatal, post-partum and family planning services at these selected health facilities during the project period. * Any eligible potential participant without a valid consent. * Any potential participant who is excluded by a doctor or midwife for a known contraindicating medical condition that can lead to potential harm to the participant or staff. Any potential participant who is unable to understand and respond to the questions being asked. Participants with proof of prior vaccination will be excluded from this part of the study.