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"Xijiang Project" Screening Cohort for NPC
Sponsor: Ming-Yuan Chen
Summary
The purpose of this study is to establish a comprehensive and integrated nasopharyngeal carcinoma screening cohort, which includes an epidemiological information database containing basic information, gender, age, ethnic and family history, dietary and lifestyle habits, and geographical environmental factors; a biobank of blood, tissue fluid, swabs, etc., for Epstein-Barr virus, tumors, and genetics; a clinical examination database including nasopharyngoscopy, imaging, pathology, and other examinations; and databases of Epstein-Barr virus and human genetic sequencing, etc.
Official title: Establishment of "Xijiang Project" Million-Person Screening Cohort for Nasopharyngeal Carcinoma
Key Details
Gender
All
Age Range
30 Years - 69 Years
Study Type
OBSERVATIONAL
Enrollment
1000000
Start Date
2024-11-14
Completion Date
2045-12
Last Updated
2025-01-22
Healthy Volunteers
Yes
Conditions
Interventions
EBV antibodies test
ELISA test of VCA-IgA, EBNA1-IgA, EA-IgA, Zta-IgA, Rta-IgG and P85-Ab in nasopharyngeal brushing and plasma in plasma, saliva and nasopharyngeal brushing.
EBV DNA test
quantitative polymerase chain reaction, methylation sequencing and target sequencing of EBV DNA in nasopharyngeal brushing, saliva and plasma.
epidemiological information survey
epidemiological information survey including basic conditions, dietary and lifestyle habits, social, geographical, environmental, and other information.
Clinical examinations for high-risk participants
nasopharyngoscopy, head and neck MRI.
EBV and human genetic sequencing
EB virus and human genetic sequencing for plasma, etc.
Locations (1)
The Fifth Affiliated Hospital of Sun Yat-sen University
Zhuhai, Guangdong, China