Clinical Research Directory

Inclusion Criteria: * Patients aged 18-65 years after metabolic bariatric surgery. * Patients will be randomly selected from the hospital's electronic patient system. Exclusion Criteria: * Allergies or Sensitivities: Patients with known allergies or hypersensitivity to collagen or any components of the collagen supplements (e.g., bovine, marine sources). * Chronic Skin Conditions: Participants with skin disorders that could influence collagen production or degradation (e.g., psoriasis, eczema, scleroderma) should be excluded as these conditions might interfere with the study's outcomes. * Autoimmune or Connective Tissue Diseases: Patients with autoimmune diseases (e.g., lupus, rheumatoid arthritis) or connective tissue disorders (e.g., Ehlers-Danlos syndrome) might exhibit abnormal collagen metabolism and could confound the study's results. * Use of Collagen or Nutritional Supplements: Participants currently taking collagen supplements or other nutritional supplements (e.g., vitamin C, glucosamine, chondroitin) that could affect collagen synthesis or turnover should be excluded. A washout period may be required for those who have recently used such supplements. * Hormonal Treatments or Medications: Patients on treatments that could affect collagen metabolism (e.g., corticosteroids, hormone replacement therapy, anabolic steroids) should be excluded, as these could alter the body's collagen production or degradation. * Pregnancy or Lactation: Pregnant or breastfeeding women should be excluded due to the physiological changes during pregnancy and lactation that could affect collagen metabolism. * Major Surgeries or Trauma: Recent major surgeries or significant trauma within the last 6-12 months, especially those involving connective tissue repair, as these could alter collagen levels independently of supplementation. * Smoking: Smokers or individuals who have recently quit smoking, as smoking is known to reduce collagen synthesis and impair skin healing. * Chronic Illnesses: Patients with chronic illnesses such as diabetes, liver disease, or kidney disease, which could impair collagen metabolism or affect skin health. * Uncontrolled Metabolic Disorders: Participants with uncontrolled metabolic disorders (e.g., severe obesity, untreated hyperlipidemia) may have altered collagen metabolism and should be excluded unless specifically studied. * Participation in Other Clinical Trials: Patients currently enrolled in other clinical trials involving supplements, medications, or procedures that could interfere with the study outcomes should be excluded.