Clinical Research Directory

Inclusion Criteria: * Men and women aged \>18 years. * Patients with a confirmed diagnosis of elevated LDL-C levels necessitating medical management. * Patients in the low to moderate cardiovascular disease (CVD) risk category according to ESC guidelines (2019) * Low-risk: Increased LDL-C level without any co-morbidities * Moderate-risk: Young patients (T1DM \<35 years; T2DM \<50 years) with DM duration \<10 years, without other risk factors. Exclusion Criteria: * History of hypersensitivity to any study drugs. * Clinically significant hepatic impairment (ALT, AST level \> 2xULN) and/or renal impairment (Serum creatinine level ≥2xULN). * Patients with hepatitis B virus (HBV) or hepatitis C virus (HCV) with cirrhosis, end-stage liver disease, cancer, psychiatric instability, HIV + status, intestinal malabsorption. * Pregnant or lactating females. * The presence of a condition that, in the opinion of the investigator, would place the subject at increased risk from study participation.