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NOT YET RECRUITING
NCT06791824
PHASE1/PHASE2

Study of CM313(SC) Injection in Subjects With Relapsed/Refractory Aplastic Anemia

Sponsor: Keymed Biosciences Co.Ltd

View on ClinicalTrials.gov

Summary

This is a randomized, open-label, phase IB/II clinical study to evaluate the safety, tolerability and preliminary efficacy of CM313(SC) injection in patients with relapsed/refractory aplastic anemia

Official title: A Phase IB/II Clinical Study to Assess the Safety, Tolerability and Preliminary Efficacy of CM313(SC) Injection in Subjects With Relapsed/Refractory Aplastic Anemia

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

125

Start Date

2025-03

Completion Date

2027-12

Last Updated

2025-02-18

Healthy Volunteers

No

Conditions

Interventions

BIOLOGICAL

CM313(SC) injection

Phase IB: CM313(SC) administered at low dose according to the protocol. Phase II: CM313(SC) administered at different doses based on Phase IB's results.

BIOLOGICAL

CM313(SC) injection

Phase IB: CM313(SC) administered at medium dose according to the protocol. Phase II: CM313(SC) administered at different doses based on Phase IB's results.

BIOLOGICAL

CM313(SC) injection

Phase IB: CM313(SC) administered at high dose according to the protocol. Phase II: CM313(SC) administered at different doses based on Phase IB's results.

Locations (1)

Institute of Hematology & Blood Diseases Hospital

Tianjin, Tianjin Municipality, China