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This Study Evaluates the Clinical Effect of Adding Spermidine Gel to Minimally Invasive Non-surgical Periodontal Therapy (MINST) to Improve Periodontal Health.
Sponsor: Luca Ramaglia
Summary
This study investigates the effectiveness of using a spermidine-based gel as an adjunct to minimally invasive non-surgical periodontal therapy (MINST) for treating periodontitis. The primary outcome is to assess whether the addition of spermidine gel reduces pocket depth (PPD) compared to MINST alone. Secondary outcome include evaluating other periodontal parameters like bleeding on probing, FMBS and FMPS and CAL over a 12-month period.
Official title: Evaluation of Subgingival Mechanical Periodontal Therapy with the Additional Local Application of a Spermidine-Based Gel
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
12
Start Date
2025-01-25
Completion Date
2026-01-20
Last Updated
2025-02-26
Healthy Volunteers
No
Conditions
Interventions
spermidine and minimally invasive non surgical tecnique
minimally non surgical periodontal therapy will be performed with the adjunct of spermidine based gel
peridontal therapy (minimally invasive non surgical tecnique)
subgingival instrumentation will be performed according to MINST
Locations (1)
AOU Federico II
Naples, Italy, Italy