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Serratus Anterior Plane and PECS II Blocks After Coronary Artery Bypass Grafting
Sponsor: Yuzuncu Yil University
Summary
This prospective randomized placebo-controlled trial was designed to evaluate the effects of ultrasound-guided bilateral pectoralis (PECS II) and serratus anterior plane (SAP) blocks on postoperative recovery in adult patients undergoing elective coronary artery bypass grafting (CABG). Patients were randomized to receive bilateral PECS II block, bilateral SAP block, or bilateral sham fascial plane injections in addition to standardized systemic analgesia. The study evaluated postoperative pain intensity using the Visual Analog Scale (VAS), opioid consumption, postoperative nausea and vomiting (PONV), block-related complications, duration of mechanical ventilation, time to first mobilization, and intensive care unit (ICU) length of stay.
Official title: Postoperative Bilateral Serratus Anterior Plane Versus PECS II Block in Intubated Patients Undergoing Elective Coronary Artery Bypass Grafting: A Prospective, Randomized, Placebo-Controlled Trial
Key Details
Gender
All
Age Range
20 Years - Any
Study Type
INTERVENTIONAL
Enrollment
243
Start Date
2022-12-05
Completion Date
2024-01-31
Last Updated
2026-08-06
Healthy Volunteers
No
Interventions
Bilateral Serratus Anterior Plane Block
Ultrasound-guided bilateral serratus anterior plane (SAP) block performed using 20 mL of 0.25% bupivacaine on each side after ICU admission while patients remained intubated following elective coronary artery bypass grafting.
Bilateral PECS II Block
Ultrasound-guided bilateral PECS II block was performed using the standard two-injection technique after ICU admission while patients remained intubated following elective coronary artery bypass grafting. On each side, a total of 20 mL of 0.25% bupivacaine was injected between the pectoralis major and minor muscles and between the pectoralis minor and serratus anterior muscles.
Sham Fascial Plane Procedure
Ultrasound-guided bilateral sham fascial plane procedure was performed after ICU admission while patients remained intubated following elective coronary artery bypass grafting. On each side, 20 mL of 0.9% saline was injected at both the PECS II and serratus anterior plane injection sites using identical coded syringes to maintain study blinding.
Locations (1)
Van Yuzuncu Yil University Faculty of Medicine Department of anesthesiology and reanimation
Van, Tuşba, Turkey (Türkiye)