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Efficacy of taVNS Versus Sham Stimulation in Reduing Depressive Symptoms in Patients With Epilepsy: a Multi-center, Double-blinded, Randomized, 20-week, Parallel-arm, Superiority Study
Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University
Summary
The purpose of this study is to compare the efficacy of taVNS versus sham stimulation in reduing depressive symptoms in patients with epilepsy.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
158
Start Date
2023-04-01
Completion Date
2025-12-31
Last Updated
2025-01-27
Healthy Volunteers
No
Interventions
Intervention
taVNS 25Hz+routine treatment, three times daily, 30 mins
Sham Comparator
taVNS 1Hz+routine treatment, three times daily, 30 mins
Locations (5)
The Second Affiliated Hospital, School of Medicine, Zhejiang University
Hangzhou, Zhejiang, China
The First People's Hospital of Jiaxing
Jiaxing, Zhejiang, China
Jinhua Second Hospital
Jinhua, Zhejiang, China
Ningbo Medical Center Li Huili Hospital
Ningbo, Zhejiang, China
The Fourth Affiliated Hospital, School of Medicine, Zhejiang University
Yiwu, Zhejiang, China