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Therapeutic Effect of Vitamin C Supplementation in Patients With Ovarian Aging
Sponsor: Peking University Third Hospital
Summary
The goal of this clinical trial is to learn if Vitamin C works to improve ovarian reserve in women with ovarian aging. It will also learn about the safety of Vitamin C. The main questions it aims to answer are: * Does Vitamin C supplementation improve the ovarian reserve prediction score? * What medical problems do participants have when taking Vitamin C supplementation? Researchers will compare Vitamin C to a placebo (a look-alike substance that contains no drug) to see if drug Vitamin C works to improve ovarian reserve in women with ovarian aging. Participants will: * Take Vitamin C or a placebo every day for 12 months * Visit the clinic once every 4 weeks for follow-up and drug distribution. * Return the Vitamin C box at each visit. * Report any adverse effects of treatment to the doctor. * Fill out a questionnaire at each visit. * After 6 months and 12 months of intervention, take blood test and ultrasonic examination.
Official title: Therapeutic Effect of Vitamin C Supplementation in Patients With Ovarian Aging：a Multicenter, Double-blind, Randomized Controlled Trial
Key Details
Gender
FEMALE
Age Range
Any - Any
Study Type
INTERVENTIONAL
Enrollment
354
Start Date
2025-07-02
Completion Date
2027-08-31
Last Updated
2025-06-26
Healthy Volunteers
No
Interventions
Vitamin C (Ascorbic Acid)
Participants swallow synthetic vitamin C tablets 500mg with water, twice a day.
Vitamin C (Ascorbic Acid)
Participants swallow naturral vitamin C tablets 500mg with water, twice a day.
Placebo
Participants swallow tablets with the same texture, flavor, and appearance as the experimental group 500mg with water, twice a day.