Clinical Research Directory
Browse clinical research sites, groups, and studies.
Early Identification and Treatment of Rare Cardiomyopathy Cohorts
Sponsor: RenJi Hospital
Summary
This study aims to further develop an imaging-guided cohort of rare cardiomyopathies based on the existing database. The investigators will standardize the construction of a cohort that integrates a clinical data repository, serum biobank, myocardial tissue bank, and imaging database. In the current cohort, the investigators will systematically screen for biomarkers indicative of pathological changes in challenging cardiomyopathies. Multidimensional data will be integrated to establish and optimize a heart failure risk assessment model, which will then be validated in a prospective cohort. The effectiveness of the model in assessing different risk groups will be evaluated, with the goal of achieving precise prevention of heart failure from the source.
Official title: Early Identification and Treatment of Rare Myocardium by Multimodal Imaging (EARLY-MYO-RARE)
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
300
Start Date
2025-02-01
Completion Date
2027-09-30
Last Updated
2025-01-27
Healthy Volunteers
No
Conditions
Interventions
diuretics, ACEIs/ARBs, beta blockers, positive inotropic drugs, MRAs, SGLT2i, retinoids
Patients in this group will receive pharmacological treatment for heart failure.
Close follow-up
High risk patients receive close follow-up
early rehabilitation guidance
Early rehabilitation guidance such as cardiopulmonary exercise tests and cardiac rehabilitation therapy
Locations (1)
Renji Hospital
Shanghai, Shanghai Municipality, China