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Study on the Impact of a Modified Mediterranean Diet, in Patients With Colorectal Cancer Undergoing Active Medical Oncology Treatment
Sponsor: Azienda Socio Sanitaria della Brianza
Summary
The study plans to evaluate the impact of the Modified Mediterranean Diet on the biodiversity of the intestinal microbiota (the set of physiological bacteria present at the intestinal level) in patients suffering from metastatic colorectal cancer undergoing chemotherapy treatment +/- biological agent, comparing the microbiota with that of patients following a Western or standard diet. Specifically, as well demonstrated in clinical studies, there are populations of bacteria that play a role in protecting the intestinal barrier and whose proliferation could be promoted by the Modified Mediterranean Diet. The study also intends to evaluate the influence of the microbiome on the clinical progress of the disease in terms of side effects and quality of life.
Official title: Randomized Pilot Study on the Impact of a Modified Mediterranean Diet (DMM) on the Intestinal Microbiota and Clinical Outcome in Patients With Colorectal Cancer Undergoing Active Medical Oncology Treatment
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2024-07-24
Completion Date
2028-07-23
Last Updated
2025-01-27
Healthy Volunteers
No
Conditions
Interventions
Nutrition
The patient will be instructed to follow the modified Mediterranean diet or his usual diet based on the assigned treatment group.
Biological samples collection
Additional biological samples will also be collected.
Locations (1)
U.O. di Oncologia di Vimercate, ASST-Brianza
Vimercate, MB, Italy