Clinical Research Directory
Browse clinical research sites, groups, and studies.
Detection of Circulating Therapeutic Monoclonal Antibodies in Biological Samples of Gynecological Cancer Patients.
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Summary
Quantification of anti PD-1 mAbs in cancer patients is extremely important to monitor pharmacokinetics and effectiveness of immunotherapy. To detect the ICI mAbs in patients' blood plasma samples, we select three anti PD-1 mAbs (cemiplimab, dostarlimab and pembrolizumab) as prognostic biomarkers which will be quantified using different biochemical/analytical assays.
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
12
Start Date
2025-03-01
Completion Date
2030-12-01
Last Updated
2025-01-28
Healthy Volunteers
No
Conditions
Interventions
Blood samples for the analysis of sildenafil in plasma
To detect the ICI mAbs in patients' blood plasma samples, we select three anti PD-1 mAbs (cemiplimab, dostarlimab and pembrolizumab) as prognostic biomarkers which will be quantified using different biochemical/analytical assays.