Clinical Research Directory
Browse clinical research sites, groups, and studies.
Unraveling the Role of Extracellular Vesicles-driven Senescence in Myeloproliferative Neoplasms
Sponsor: IRCCS Azienda Ospedaliero-Universitaria di Bologna
Summary
In this study the aim is to investigate the pathogenetic role of extracellular vesicles and senescence in Myeloproliferative Neoplasms. In particular, the goal of this project is to identify possible EV-based biomarkers of senescence according to gender, which are disease-specific, biology-related, and predictive of short-term outcome in terms of Event-Free Survival and to define personalized targets for new therapeutic approaches.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
110
Start Date
2022-02-15
Completion Date
2025-08
Last Updated
2025-01-29
Healthy Volunteers
Yes
Locations (5)
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Bologna, Bologna, Italy
ASST Spedali Civili di Brescia
Brescia, BS, Italy
Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori- IRST
Meldola, FC, Italy
Ospedale S.Maria delle Croci
Ravenna, RA, Italy
Arcispedale S. Maria Nuova - IRCCS
Reggio Emilia, RE, Italy