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NCT06798805

Unraveling the Role of Extracellular Vesicles-driven Senescence in Myeloproliferative Neoplasms

Sponsor: IRCCS Azienda Ospedaliero-Universitaria di Bologna

View on ClinicalTrials.gov

Summary

In this study the aim is to investigate the pathogenetic role of extracellular vesicles and senescence in Myeloproliferative Neoplasms. In particular, the goal of this project is to identify possible EV-based biomarkers of senescence according to gender, which are disease-specific, biology-related, and predictive of short-term outcome in terms of Event-Free Survival and to define personalized targets for new therapeutic approaches.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

110

Start Date

2022-02-15

Completion Date

2025-08

Last Updated

2025-01-29

Healthy Volunteers

Yes

Locations (5)

IRCCS Azienda Ospedaliero-Universitaria di Bologna

Bologna, Bologna, Italy

ASST Spedali Civili di Brescia

Brescia, BS, Italy

Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori- IRST

Meldola, FC, Italy

Ospedale S.Maria delle Croci

Ravenna, RA, Italy

Arcispedale S. Maria Nuova - IRCCS

Reggio Emilia, RE, Italy