Clinical Research Directory

Inclusion Criteria: 1. Able to communicate with investigator, and to provide informed consent and have signed Informed Consent Form (ICF) prior to screening procedures 2. Adults aged 19 to 40 years 3. Judged to be healthy by the Investigator on the basis of medical history, physical examination, screening laboratory results and vital signs performed at screening visit 4. Able and willing to comply with all study procedures during the study period 5. Negative serological tests for Hepatitis B surface antigen (HBsAg), Hepatitis B surface antibody (Anti-HBs), antibody to Hepatitis B core antibody (anti-HBc), Hepatitis C antibody and Human Immunodeficiency Virus (HIV) antibody at screening Exclusion Criteria: 1. Pregnant or breastfeeding, or intending to become pregnant or father children within the projected duration of the trial starting with the screening visit until 3 months following last dose 2. Positive serum pregnancy test at screening or positive urine pregnancy test prior at dosing visit 3. Self-reported history of Hepatitis B vaccination beyond childhood Hepatitis B immunization series 4. Currently participating in or has participated in a study with an investigational product administered within 6 months preceding Day 0 5. Body mass index (BMI) \<18 or \>30 kg/m² 6. Current or history of the following medical conditions: * Diagnosis of malignancy within 5 years of screening * Diagnosis of diabetes mellitus or HbA1c ≥7% * Liver transaminases \> 2 times the upper limit of the normal range * Impaired renal function as creatinine \>120 mmol/L or calculated glomerular filtration rate \<60mls/min * Use of immunoglobulin or blood products in last 3 months * History of severe allergic reaction or anaphylaxis after immunization or administration of any medical products that contain drug substances of investigational product