Clinical Research Directory

Inclusion Criteria: * Body mass index between 18.5 - 24.9 kg/m2 * Non-diabetic * Blood pressure (≤140/90 mmHg) * \<5% weight change in the past 6 months * Fasting triglyceride \< 90 mg/dl and HOMA-IR ≤ 1.0 will be defined as healthy subjects * Fasting triglyceride ≥ 90 mg/dl and HOMA-IR \> 1.0 will be defined as MONW subjects Exclusion Criteria: * • Smoker or currently on nicotine therapy * Regularly consume alcohol \>1 unit per day * On hypocaloric/hypercaloric diet aiming for weight loss/gain * An athlete or sportive person with regular exercising \>3 times per week and \>45 minutes per section. * Currently receiving therapy (e.g. insulin) or any medication/ treatment (including supplements) that may affect glucose and lipid metabolism, energy metabolism or body composition * Currently on steroids, protease inhibitors, or antipsychotics therapies * Has symptomatic Irritable Bowel Syndrome * Has glucose-6-phosphate dehydrogenase (G6PD) deficiency * Had major medical or surgical event requiring hospitalization within the preceding 3 months * Participated in drug trials within 3 months before the start of the study * Donated blood within 3 months before the start of the study * Has intolerances or allergies to any of the study foods (eg. anaphylaxis to glutens) * Pregnant (pregnancy test will be done), lactating, or planning to be become pregnant during the study period * Has active Tuberculosis (TB) or currently receiving treatment for TB * Has chronic infection or is known to suffer from or has previously suffered from or is a carrier of Hepatitis B Virus (HBV), Hepatitis C Virus (HCV), Human Immunodeficiency Virus (HIV) * Has claustrophobia, trypanophobia, or hemophobia * Unwilling to consume study foods * Inadequate fluency in the English language * Unable to understand the study procedures and signs forms providing written informed consent to participate in the study. * Is a member of the research team or their immediate family members. Immediate family member is defined as a spouse, parent, child, or sibling, whether biological or legally adopted